HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 58614812, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 58614938 | HCID 58614938 | — |
| Product | HCID 58614812 | HCID 58614812 | — |
Reaction Steps
N-(4-chloro-3-(5-hydroxypyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide (0.12 mmol) was used in Procedure L with excess iodomethane. Purified by silica gel chromatography (0-100% ethyl acetate/hexane) to yield N-(4-chloro-3-(5-methoxypyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide as a white solid: TLC Rf=0.57 (50% ethyl acetate/hexanes); MS (Q1) 423 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321761B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-8c74d4842717422eb1d3f9071b1986da |
| Source note | uspto-grants-2016_04 |