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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 633056Generated: October 30, 2026

4,5-Dihydro-2-thiazolamine → HCID 58614922, compound

https://huagongshe.com/reaction/633056

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,5-Dihydro-2-thiazolamineHCID 15689—
Reactant3-Chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acidHCID 66878605—
ProductHCID 58614922HCID 58614922—

Reaction Steps

50 mg of 3-chloro-4-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)benzoic acid was coupled to 2-amino-4,5-dihydrothiazole via Procedure G. The product was purified on reverse phase HPLC to yield 2-chloro-N1-(4-chloro-3-(pyridin-2-yl)phenyl)-N4-(4,5-dihydrothiazol-2-yl)terephthalamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321761B2
Source datasetuspto-grants-2016_04
ORD IDord-675e8cf9a7e84e6e8cd4e1b338da0723
Source noteuspto-grants-2016_04