Acetonitrile → HCID 86694609, compound

HRID 63318Notes

Reaction equation

[CH2:1]([CH:4]([CH2:17][CH2:18][CH3:19])[CH2:5][O:6][C:7]1[N:12]=[C:11]([C:13]([O:15]C)=O)[CH:10]=[CH:9][CH:8]=1)[CH2:2][CH3:3].[CH3:20][C:21]#[N:22]>>[O:15]=[C:13]([C:11]1[CH:10]=[CH:9][CH:8]=[C:7]([O:6][CH2:5][CH:4]([CH2:1][CH2:2][CH3:3])[CH2:17][CH2:18][CH3:19])[N:12]=1)[CH2:20][C:21]#[N:22]

Participants

Reactant 2

HCID 6342Acetonitrile

HCID 86694610HCID 86694610, compound

Product 1

HCID 86694609HCID 86694609, compound

Procedure

CH3CN addition to methyl 6-((2-propylpentyl)oxy)picolinate following the method used in Example 6 gave 3-oxo-3-(6-((2-propylpentyl)oxy)pyridin-2-yl)propanenitrile in quantitative yield as a solid which was directly used in next reaction without further purification.

Sources & evidence

ORD record: ord-8b1dd8105cea4bf08a74bfd40cfa7d6f
Source dataset: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09447078B2

Reaction notes

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