HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chlorosulfonyl)benzoic acid → HCID 58614628, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chlorosulfonyl)benzoic acid | HCID 82385 | — |
| Reactant | 4-((4-Hydroxypiperidin-1-yl)sulfonyl)benzoic acid | HCID 18071808 | — |
| Reactant | 4-Chloro-3-(pyridin-2-yl)aniline | HCID 40151925 | — |
| Solvent | Piperidin-4-ol | HCID 79341 | — |
| Product | HCID 58614628 | HCID 58614628 | — |
Reaction Steps
1 g of 4-(chlorosulfonyl)benzoic acid was reacted with 506 μL of piperidin-4-ol via Procedure H. 75 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 114 mg of 4-(4-hydroxypiperidin-1-ylsulfonyl)benzoic acid via Procedure G and purified by reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(4-hydroxypiperidin-1-ylsulfonyl)benzamide. MS (Q1) 472.3 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321761B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-00ec9409b5ef4910a3d1982c8fe88810 |
| Source note | uspto-grants-2016_04 |