HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Hydroxyethanesulfonyl)benzoic acid → HCID 58614656, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Hydroxyethanesulfonyl)benzoic acid | HCID 14365570 | — |
| Reactant | 4-Chloro-3-(pyridin-2-yl)aniline | HCID 40151925 | — |
| Product | HCID 58614656 | HCID 58614656 | — |
Reaction Steps
Procedure T to give 4-(2-hydroxyethylthio)benzoic acid. 1.0 g of 4-(2-hydroxyethylthio)benzoic acid was reacted via Procedure R to give 4-(2-hydroxyethylsulfonyl)benzoic acid. 80 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 4-(2-hydroxyethylsulfonyl)benzoic acid via Procedure G. The product was purified on reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(2-hydroxyethylsulfonyl)benzamide. MS (Q1) 417.0 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321761B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-74ef52c793404cbcb66a7858468bfe9a |
| Source note | uspto-grants-2016_04 |