HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperazine, (R)- → HCID 58614709, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperazine, (R)- | HCID 7330434 | — |
| Reactant | 6-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methylnicotinamide | HCID 58614798 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 58614709 | HCID 58614709 | — |
Reaction Steps
Procedure F was performed using 100 mg of 6-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methylnicotinamide and 112 mg of R-(+)-2-methylpiperizine in 1 mL of BuOH. Purified by reverse phase HPLC to yield (R)—N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methyl-6-(3-methylpiperazin-1-yl)nicotinamide. MS (Q1) 422.3 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321761B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-8ca09c05994741d5932d92b3a58f3cfd |
| Source note | uspto-grants-2016_04 |