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HRID633297

反应详情

EQUATION

反应方程式

HRID 633297 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)N1CCNCC1
HCID83795

1-Acetylpiperazine

C6H12N2O

结构：Cc1nc(Cl)ccc1C(=O)Nc1ccc(Cl)c(-c2ccccn2)c1
HCID58614798

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)N1CCN(c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)c(C)n2)CC1
HCID50898448

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCO
溶剂HCID263

1-Butanol

C4H10O

PROCEDURE

实验过程

Procedure F was performed using 55 mg of 6-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methylnicotinamide and 99 mg of 1-acetylpiperazine in 0.5 mL of BuOH. Purified by reverse phase HPLC to yield 6-(4-acetylpiperazin-1-yl)-N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methylnicotinamide. MS (Q1) 450.4 (M)+.

WORKUP

后处理

  1. customPurified by reverse phase HPLC