Acetonitrile → HCID 86694631, compound

HRID 63331Notes

Reaction equation

HRID 63331 reaction equation
[CH2:1]([CH:3]([CH2:16][CH3:17])[CH2:4][O:5][C:6]1[N:11]=[C:10]([C:12]([O:14]C)=O)[CH:9]=[CH:8][CH:7]=1)[CH3:2].[CH3:18][C:19]#[N:20]>>[CH2:16]([CH:3]([CH2:1][CH3:2])[CH2:4][O:5][C:6]1[N:11]=[C:10]([C:12](=[O:14])[CH2:18][C:19]#[N:20])[CH:9]=[CH:8][CH:7]=1)[CH3:17]

Participants

3

Reactant 2

HCID 6342AcetonitrileHCID 86694632HCID 86694632, compound

Product 1

HCID 86694631HCID 86694631, compound

Procedure

CH3CN addition to methyl 6-(2-ethylbutoxy)picolinate following the method described in Example 6 gave 3-(6-(2-ethylbutoxy)pyridin-2-yl)-3-oxopropanenitrile as a yellow oil which was used in the next step without further purification. Yield (1.2 g, quant.).

Sources & evidence

ORD record
ord-4e5d22841c7c493fa3dfbc3034e9bc21
Source dataset
uspto-grants-2016_09
Patent number
US09447078B2

Reaction notes

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