HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-6-(trifluoromethyl)nicotinoyl chloride → HCID 58614781, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-6-(trifluoromethyl)nicotinoyl chloride | HCID 2775675 | — |
| Reactant | 3-Amino-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonylmethyl)benzamide | HCID 58614887 | — |
| Product | HCID 58614781 | HCID 58614781 | 36.9% |
Reaction Steps
3-Amino-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonylmethyl)benzamide (30 mg, 0.072 mmol) was reacted with 2-methyl-6-(trifluoromethyl)nicotinoyl chloride (19 mg, 0.079 mmol) via procedure V to afford 16 mg of N-(5-(4-chloro-3-(pyridin-2-yl)phenylcarbamoyl)-2-(methylsulfonylmethyl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide as a white solid. MS (Q1) 603 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321761B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-0fd38d1f8e45432982d23cd326c85e42 |
| Source note | uspto-grants-2016_04 |