Acetonitrile → HCID 86694634, compound

HRID 63333Notes

Reaction equation

HRID 63333 reaction equation
[CH:1]1([CH2:8][O:9][C:10]2[N:15]=[C:14]([C:16]([O:18]C)=O)[CH:13]=[CH:12][CH:11]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:20][C:21]#[N:22]>>[CH:1]1([CH2:8][O:9][C:10]2[N:15]=[C:14]([C:16](=[O:18])[CH2:20][C:21]#[N:22])[CH:13]=[CH:12][CH:11]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 6342AcetonitrileHCID 86694635HCID 86694635, compound

Product 1

HCID 86694634HCID 86694634, compound

Procedure

CH3CN addition to methyl 6-(cycloheptylmethoxy)picolinate following the method used in Example 6 gave 3-(6-(cycloheptylmethoxy)pyridin-2-yl)-3-oxopropanenitrile as a yellow oil which was used in the next step without further purification. Yield (2.12 g, quant.).

Sources & evidence

ORD record
ord-a25e6baba5454d37b926c3ad3b0bf60d
Source dataset
uspto-grants-2016_09
Patent number
US09447078B2

Reaction notes

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