Acetonitrile → HCID 86694658, compound

HRID 63346Notes

Reaction equation

HRID 63346 reaction equation
[O:1]1[CH2:6][CH2:5][CH:4]([CH2:7][O:8][C:9]2[N:14]=[C:13]([C:15]([O:17]C)=O)[CH:12]=[CH:11][CH:10]=2)[CH2:3][CH2:2]1.[CH3:19][C:20]#[N:21]>>[O:17]=[C:15]([C:13]1[CH:12]=[CH:11][CH:10]=[C:9]([O:8][CH2:7][CH:4]2[CH2:3][CH2:2][O:1][CH2:6][CH2:5]2)[N:14]=1)[CH2:19][C:20]#[N:21]

Participants

3

Reactant 2

HCID 6342AcetonitrileHCID 86694659HCID 86694659, compound

Product 1

HCID 86694658HCID 86694658, compound

Procedure

Reaction between methyl 6-((tetrahydro-2H-pyran-4-yl)methoxy)picolinate and CH3CN following the method used in Example 6 gives 3-oxo-3-(6-((tetrahydro-2H-pyran-4-yl)methoxy)pyridin-2-yl)propanenitrile.

Sources & evidence

ORD record
ord-388c0633602243298b40c7dd1e4539ef
Source dataset
uspto-grants-2016_09
Patent number
US09447078B2

Reaction notes

Loading…