Aluminium lithium hydride → HCID 86694660, compound

HRID 63347Notes

Reaction equation

HRID 63347 reaction equation
[O:1]=[C:2]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH2:13][CH:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)[N:7]=1)[CH2:3][C:4]#[N:5].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[NH2:5][CH2:4][CH2:3][CH:2]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH2:13][CH:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[N:7]=1)[OH:1]

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 86694658HCID 86694658, compound

Product 1

HCID 86694660HCID 86694660, compound

Procedure

Reduction of 3-oxo-3-(6-((tetrahydro-2H-pyran-4-yl)methoxy)pyridin-2-yl)propanenitrile by LiAlH4 following the method used in Example 2 gives Example 38.

Workup

  1. customgives Example 38

Sources & evidence

ORD record
ord-52851dd686ff4bcab5f20d96f3387d3b
Source dataset
uspto-grants-2016_09
Patent number
US09447078B2

Reaction notes

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