Acetonitrile → HCID 86694661, compound

HRID 63348Notes

Reaction equation

HRID 63348 reaction equation
[CH2:1]([O:9][C:10]1[N:15]=[C:14]([C:16]([O:18]C)=O)[CH:13]=[CH:12][CH:11]=1)[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:20][C:21]#[N:22]>>[O:18]=[C:16]([C:14]1[CH:13]=[CH:12][CH:11]=[C:10]([O:9][CH2:1][CH2:2][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:15]=1)[CH2:20][C:21]#[N:22]

Participants

3

Reactant 2

HCID 6342AcetonitrileHCID 86694662HCID 86694662, compound

Product 1

HCID 86694661HCID 86694661, compound

Procedure

CH3CN addition to methyl 6-phenethoxypicolinate following the method described in Example 6 gave 3-oxo-3-(6-phenethoxypyridin-2-yl)propanenitrile as a yellow oil which was used in the next step without further purification. Yield (1.33 g, quant.).

Sources & evidence

ORD record
ord-29d9f0f9c0f747148cf1159d03a55913
Source dataset
uspto-grants-2016_09
Patent number
US09447078B2

Reaction notes

Loading…