HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dimercapto-2,3-butanediol → 2-Morpholin-4-ylethyl (6-sulphanyl-1,3-benzothiazol-2-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dimercapto-2,3-butanediol | HCID 19001 | — |
| Reactant | 2-Morpholin-4-ylethyl (6-thiocyanato-1,3-benzothiazol-2-yl)carbamate | HCID 86707006 | — |
| Catalyst | Monobasic potassium phosphate | HCID 516951 | — |
| Product | 2-Morpholin-4-ylethyl (6-sulphanyl-1,3-benzothiazol-2-yl)carbamate | HCID 86707005 | 173.7% |
Reaction Steps
The 2-morpholin-4-ylethyl (6-sulphanyl-1,3-benzothiazol-2-yl)carbamate was prepared according to the method described in Example 1b, but using 547 mg of 2-morpholin-4-ylethyl (6-thiocyanato-1,3-benzothiazol-2-yl)carbamate, 12 mg of potassium dihydrogen phosphate and 1.16 g of DL-dithiothreitol. 885 mg of 2-morpholin-4-ylethyl (6-sulphanyl-1,3-benzothiazol-2-yl)carbamate are thus obtained in the form of a white solid, the characteristics of which are as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321777B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-48aab0433a234f78a9ca483ca94cb326 |
| Source note | uspto-grants-2016_04 |