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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63353Generated: October 30, 2026

Acetonitrile → 3-(2-(Cyclohexylmethoxy)pyrimidin-4-yl)-3-hydroxypropanenitrile

https://huagongshe.com/reaction/63353

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
Reactant2-(Cyclohexylmethoxy)pyrimidine-4-carbaldehydeHCID 86694668—
Product3-(2-(Cyclohexylmethoxy)pyrimidin-4-yl)-3-hydroxypropanenitrileHCID 86694669—

Reaction Steps

CH3CN addition to 2-(cyclohexylmethoxy)pyrimidine-4-carbaldehyde following the method described in Example 6 gives 3-(2-(cyclohexylmethoxy)pyrimidin-4-yl)-3-hydroxypropanenitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447078B2
Source datasetuspto-grants-2016_09
ORD IDord-a7400561dd554bedba017a8011c12e1f
Source noteuspto-grants-2016_09