HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl[4-(7-chloro-5-methylsulfanyloxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethylphenoxy]acetate → tert-Butyl [4-(7-isobutyl-5-methylsulfanyloxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethylphenoxy]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl[4-(7-chloro-5-methylsulfanyloxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethylphenoxy]acetate | HCID 89350956 | — |
| Reactant | HCID 178418816 | HCID 178418816 | — |
| Product | tert-Butyl [4-(7-isobutyl-5-methylsulfanyloxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethylphenoxy]acetate | HCID 71187291 | 20% |
Reaction Steps
Analogously to example 1 (g), the reaction of 1.50 g of tert-butyl [4-(7-chloro-5-methylsulfanyloxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethylphenoxy]acetate with isobutylmagnesium bromide gave 0.31 g (20%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321787B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-a01e22f6206641cb8ab248d020958679 |
| Source note | uspto-grants-2016_04 |