HCID 71185992, compound → HCID 71203184, compound

Participants

Reaction Steps

10 mg of palladium on carbon (10%) were added to a solution of 50 mg of {4-[5-(4-chlorobenzyl)-7-isobutyloxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethylphenoxy}acetic acid, and the mixture was hydrogenated at 5 bar overnight. Three times, another 10 mg of palladium on carbon (10%) were added and the mixture was in each case hydrogenated for a day. For work-up, the catalyst was filtered off through Celite and the solution obtained was concentrated. The residue was purified by HPLC. This gave 7 mg (18%) of the title compound.

Provenance & Evidence