HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 7-(2-Cyano-benzyl)-xanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Reactant | 2-Amino-7-(2-cyano-benzyl)-1,7-dihydro-purin-6-one | HCID 136065587 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 7-(2-Cyano-benzyl)-xanthine | HCID 57519423 | — |
Reaction Steps
Prepared by treating 16.68 g of 2-amino-7-(2-cyano-benzyl)-1,7-dihydro-purin-6-one with 17.00 g of sodium nitrite in a mixture of 375 ml of conc. acetic acid, 84 ml of water and 5.2 ml of conc. hydrochloric acid at 50° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321791B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-6ef0c76641af4951b407cb0fb9a076df |
| Source note | uspto-grants-2016_04 |