HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Boc-4-(aminomethyl)piperidine → 3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid [1-(6-methoxy-3,4-dihydro-2H-1-oxa-9-aza-phenanthren-3-ylmethyl)-piperidin-4-ylmethyl]-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Boc-4-(aminomethyl)piperidine | HCID 736817 | — |
| Edukt | 3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid | HCID 760993 | — |
| Edukt | 3-bromomethyl-6-methoxy-3,4-dihydro-2H-1-oxa-9-aza-phenanthrene | HCID 86730701 | — |
| Produkt | 3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid [1-(6-methoxy-3,4-dihydro-2H-1-oxa-9-aza-phenanthren-3-ylmethyl)-piperidin-4-ylmethyl]-amide | HCID 71475483 | — |
Reaktionsschritte
The titled compound is prepared as an off-white lyophilized powder following Scheme 1 and in analogy to Example 1 using 3-bromomethyl-6-methoxy-3,4-dihydro-2H-1-oxa-9-aza-phenanthrene, 4-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester and 3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid as starting material.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09321788B2 |
| Quelldatensatz | uspto-grants-2016_04 |
| ORD ID | ord-41dd737fe7cd445c89456a7f38af6aef |
| Quellennotiz | uspto-grants-2016_04 |