Diphenyl Ether → HCID 178439550, compound

Participants

Reaction Steps

A solution of 4-allyloxy-6-methoxy-quinoline (4.0 g, 18.6 mmol, 1.0 eq) in diphenyl oxide (80 mL) is heated at 180° C. for 1 hour. The reaction mixture is then cooled down to room temperature before the addition of petroleum ether (100 mL). The resulting suspension is filtered to afford 3-allyl-6-methoxy-quinolin-4-ol as a light grey solid (1.3 g, 32% yield).

Provenance & Evidence