反应详情

2-(furan-3-yl)-4,6-dimethylphenol (Compound 6-2) (0.6 g, 3.2 mmol) was dissolved in methanol. Palladium carbon (0.06 g) was added thereto, followed by stirring under hydrogen balloon at room temperature for 6 hours. After the completion of the reaction, the reaction mixture was filtered through Celite. The filtrate was concentrated under reduced pressure, and purified by column chromatography to obtain 2,4-dimethyl-6-(tetrahydrofuran-3-yl)phenol (0.45 g, 73%).

1. customAfter the completion of the reaction
2. filtrationthe reaction mixture was filtered through Celite
3. concentrationThe filtrate was concentrated under reduced pressure
4. custompurified by column chromatography