Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 63390Generated: October 30, 2026

2-(2-Furanyl)-4,6-dimethylphenol → 2,4-Dimethyl-6-(tetrahydrofuran-2-yl)phenol

https://huagongshe.com/reaction/63390

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Furanyl)-4,6-dimethylphenolHCID 90002795—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
Product2,4-Dimethyl-6-(tetrahydrofuran-2-yl)phenolHCID 9000258198.1%

Reaction Steps

2-(furan-2-yl)-4,6-dimethylphenol (Compound 6-18) (200 mg, 1.06 mmol) were dissolved in methanol 3 mL. Palladium carbon (30 mg) was added thereto, followed by stirring under hydrogen balloon for 12 hours. After the completion of the reaction, the reaction mixture was filtered through Celite. The filtrate was concentrated under reduced pressure to obtain 2,4-dimethyl-6-(tetrahydrofuran-2-yl)phenol (200 mg, 98%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09447083B2
Source datasetuspto-grants-2016_09
ORD IDord-4b7de1dd2efe48be9ceb5ed85cbbaa72
Source noteuspto-grants-2016_09