HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Furanyl)-4,6-dimethylphenol → 2,4-Dimethyl-6-(tetrahydrofuran-2-yl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Furanyl)-4,6-dimethylphenol | HCID 90002795 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2,4-Dimethyl-6-(tetrahydrofuran-2-yl)phenol | HCID 90002581 | 98.1% |
Reaction Steps
2-(furan-2-yl)-4,6-dimethylphenol (Compound 6-18) (200 mg, 1.06 mmol) were dissolved in methanol 3 mL. Palladium carbon (30 mg) was added thereto, followed by stirring under hydrogen balloon for 12 hours. After the completion of the reaction, the reaction mixture was filtered through Celite. The filtrate was concentrated under reduced pressure to obtain 2,4-dimethyl-6-(tetrahydrofuran-2-yl)phenol (200 mg, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447083B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-4b7de1dd2efe48be9ceb5ed85cbbaa72 |
| Source note | uspto-grants-2016_09 |