Methanol → 2,6-Dimethyl-4-(tetrahydro-3-furanyl)phenol

Participants

Reaction Steps

4-(furan-3-yl)-2,6-dimethylphenol (Compound 6-5) (110 mg, 0.74 mmol) were dissolved in tetrahydrofuran:methanol=1 mL:1 mL. Palladium carbon (15 mg, 15%) was added thereto, followed by stirring under hydrogen balloon for 18 hours. After the completion of the reaction, the reaction mixture was filtered through Celite. The filtrate was concentrated under reduced pressure to obtain 2,6-dimethyl-4-(tetrahydrofuran-3-yl)phenol (74 mg, 72%).

Provenance & Evidence