HCID 86725101, compound → HCID 68328327, compound

Participants

Reaction Steps

To a solution of tert-butyl 5-(5-azido-1,3,4-thiadiazol-2-yl)-3-(6-morpholinopyridin-2-yl)-1H-indole-1-carboxylate (224 mg, 0.444 mmol) in MeOH/THF (5 mL, 3:2) was added Lindlar catalyst (59.2 mg, 0.222 mmol). The mixture was stirred at RT under hydrogen for 15 h, then filtered through a plug of celite and washed with DCM/MeOH. The filtrated was concentrated to give the crude material. MS (ESI, pos. ion) m/z: 479 (M+1).

Provenance & Evidence