HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 178519205, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-(Bromomethyl)-4-(2-fluorophenyl)-1H-isochromen-1-one | HCID 118131273 | — |
| Reactant | HCID 178519204 | HCID 178519204 | — |
| Reactant | HCID 178527205 | HCID 178527205 | — |
| Product | HCID 178519205 | HCID 178519205 | 73.5% |
Reaction Steps
The title compound was made in a similar way as that of the compound of example 10, 3-(bromomethyl)-4-(2-fluorophenyl)-1H-isochromen-1-one (intermediate C2, 37 mg, 0.111 mmol), 9H-purine-6-thiol hydrate (18.90 mg, 0.111 mmol) and K2CO3 (15.35 mg, 0.111 mmol) to give the title compound (33 mg, 73.5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321776B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-8710b71ecd4b4c4ca5b6b6a678cadf03 |
| Source note | uspto-grants-2016_04 |