HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 118131090, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1H-Pyrazolo[3,4-d]pyrimidin-4-amine | HCID 75420 | — |
| Reactant | HCID 118131033 | HCID 118131033 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 118131090 | HCID 118131090 | 54% |
Reaction Steps
The title compound was made in a similar way as that of the compound of example 15, 3-(1-bromoethyl)-4-(3-(morpholinosulfonyl)phenyl)-1H-isochromen-1-one (intermediate C9, 90 mg, 0.188 mmol), 1H-pyrazolo[3,4-d]pyrimidin-4-amine (50.8 mg, 0.376 mmol) and K2CO3 (52 mg, 0.376 mmol) in DMF (1 ml) at 80° C. for 2 hrs to give the title compound (54 mg, 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321776B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-b8a774a93a8442c1809e772a6d87a1f2 |
| Source note | uspto-grants-2016_04 |