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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 634445Generated: October 29, 2026

Potassium Carbonate → HCID 118131090, compound

https://huagongshe.com/reaction/634445

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant1H-Pyrazolo[3,4-d]pyrimidin-4-amineHCID 75420—
ReactantHCID 118131033HCID 118131033—
SolventDimethylformamideHCID 6228—
ProductHCID 118131090HCID 11813109054%

Reaction Steps

The title compound was made in a similar way as that of the compound of example 15, 3-(1-bromoethyl)-4-(3-(morpholinosulfonyl)phenyl)-1H-isochromen-1-one (intermediate C9, 90 mg, 0.188 mmol), 1H-pyrazolo[3,4-d]pyrimidin-4-amine (50.8 mg, 0.376 mmol) and K2CO3 (52 mg, 0.376 mmol) in DMF (1 ml) at 80° C. for 2 hrs to give the title compound (54 mg, 54%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321776B2
Source datasetuspto-grants-2016_04
ORD IDord-b8a774a93a8442c1809e772a6d87a1f2
Source noteuspto-grants-2016_04