HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 118131024, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1H-Pyrazolo[3,4-d]pyrimidin-4-amine | HCID 75420 | — |
| Reactant | HCID 118131409 | HCID 118131409 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 118131024 | HCID 118131024 | 3% |
Reaction Steps
The title compound was made in a similar way as that of the compound of example 15, 3-(1-bromoethyl)-4-(2-methylpyridin-4-yl)-1H-isochromen-1-one (intermediate C14, 98 mg, 0.285 mmol), 1H-pyrazolo[3,4-d]pyrimidin-4-amine (57.7 mg, 0.43 mmol) and K2CO3 (59 mg, 0.42 mmol) in DMF (2 ml) at 50° C. for 6 hrs to give the title compound (3.4 mg, 3%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321776B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-2d3fe5a547814a2c9cb0602e723cc3c3 |
| Source note | uspto-grants-2016_04 |