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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 634449Generated: October 29, 2026

Potassium Carbonate → HCID 118131205, compound

https://huagongshe.com/reaction/634449

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant1H-Pyrazolo[3,4-d]pyrimidin-4-amineHCID 75420—
ReactantHCID 118131091HCID 118131091—
SolventDimethylformamideHCID 6228—
ProductHCID 118131205HCID 11813120535.4%

Reaction Steps

The title compound was made in a similar way as that of the compound of example 15, 4-benzyl-3-(1-bromoethyl)-1H-isochromen-1-one (intermediate C13, 22 mg, 0.064 mmol), 1H-pyrazolo[3,4-d]pyrimidin-4-amine (12.99 mg, 0.096 mmol), and K2CO3 (13.29 mg, 0.096 mmol) in DMF (1 ml) at 55° C. for 2 hrs to give the title compound (9 mg, 35%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321776B2
Source datasetuspto-grants-2016_04
ORD IDord-24dbf636de18467cae03398624cf4285
Source noteuspto-grants-2016_04