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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 634476Generated: October 29, 2026

2-Methoxy-6-(tributylstannyl)pyrazine → HCID 178438189, compound

https://huagongshe.com/reaction/634476

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methoxy-6-(tributylstannyl)pyrazineHCID 16427103—
Reactant3-(1-(4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-4-phenyl-1H-isochromen-1-oneHCID 118131053—
ProductHCID 178438189HCID 17843818936.8%

Reaction Steps

The title compound was made in a similar way as that of the compound of example 89 from 3-(1-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-4-phenyl-1H-isochromen-1-one (intermediate D2a, 120 mg, 0.236 mmol) and 2-methoxy-6-(tributylstannyl)pyrazine (188 mg, 0.471 mmol) to give the title compound (25 mg, 36.8%) as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321776B2
Source datasetuspto-grants-2016_04
ORD IDord-76c44539010a4c5eb52b826d6e1e7936
Source noteuspto-grants-2016_04