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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 634480Generated: October 30, 2026

7-Deazaadenine → 3-(1-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)-4-phenyl-1H-isochromen-1-one

https://huagongshe.com/reaction/634480

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-DeazaadenineHCID 5359620—
Reactant3-(1-Bromoethyl)-4-phenyl-1H-isochromen-1-oneHCID 118131075—
Product3-(1-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)-4-phenyl-1H-isochromen-1-oneHCID 11813110728%

Reaction Steps

The title compound was made in a similar way as that of the compound of example 1 using 3-(1-bromoethyl)-4-phenyl-1H-isochromen-1-one (intermediate C7, 50 mg, 0.15 mmol), 7H-pyrrolo[2,3-d]pyrimidin-4-amine (30.6 mg, 0.23 mmol) to give the title compound (16 mg, 28%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09321776B2
Source datasetuspto-grants-2016_04
ORD IDord-c3038c22a481451f8ce8bef2ba4f7784
Source noteuspto-grants-2016_04