HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Deazaadenine → 3-(1-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)-4-phenyl-1H-isochromen-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Deazaadenine | HCID 5359620 | — |
| Reactant | 3-(1-Bromoethyl)-4-phenyl-1H-isochromen-1-one | HCID 118131075 | — |
| Product | 3-(1-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl)-4-phenyl-1H-isochromen-1-one | HCID 118131107 | 28% |
Reaction Steps
The title compound was made in a similar way as that of the compound of example 1 using 3-(1-bromoethyl)-4-phenyl-1H-isochromen-1-one (intermediate C7, 50 mg, 0.15 mmol), 7H-pyrrolo[2,3-d]pyrimidin-4-amine (30.6 mg, 0.23 mmol) to give the title compound (16 mg, 28%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09321776B2 |
| Source dataset | uspto-grants-2016_04 |
| ORD ID | ord-c3038c22a481451f8ce8bef2ba4f7784 |
| Source note | uspto-grants-2016_04 |