Potassium Phosphate, Tribasic → HCID 117818114, compound

Participants

Reaction Steps

N-phenyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)dibenzo[b,d]furan-2-amine (3.25 g, 7.0 mol), and 3-bromo-9H-carbazole (1.73 g, 7.0 mmol) were mixed in 45 mL of toluene and 15 ml of ethanol. To the solution was bubbled with nitrogen for 15 min. Pd2(dba)3 (0.16 g, 0.18 mmol), 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl (0.29 g, 7.0 mmol) and K3PO4 (4.49 g, 21.1 mmol) were added. The mixture was refluxed overnight under nitrogen. After cooling, aqueous layer was removed from the reaction mixture and dry over magnesium sulfate, and was filtered through filter paper and the filtrate was then evaporated. The residue was then purified by column chromatography using THF:hexane (1:3, v/v) as eluent 3.0 g (85%) of a white solid was obtained as the product.

Provenance & Evidence