反应详情

24.10 g (97.92 mmol) of 3-bromo-9H-carbazole 22, 30.93 g (107.71 mmol) of compound 25 and 11.56 g of sodium carbonate are suspended in 2500 ml of dioxane, 2500 ml of toluene and 1000 ml of water. 5.79 g (5.01 mmol) of Pd(PPh3)4 are added to this suspension. The reaction mixture is heated under reflux for 5 h. After cooling, the precipitated solid is filtered off with suction, washed with water and ethanol and dried. The residue is extracted with hot toluene and recrystallised from toluene. The yield is 22.0 g (55%).

1. temperatureThe reaction mixture is heated
2. temperatureunder reflux for 5 h
3. temperatureAfter cooling
4. filtrationthe precipitated solid is filtered off with suction
5. washwashed with water and ethanol
6. customdried
7. extractionThe residue is extracted with hot toluene
8. customrecrystallised from toluene