HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21260309, compound → HCID 21260327, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21260309 | HCID 21260309 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 21260327 | HCID 21260327 | 97% |
Reaction Steps
A mixture of 2,4-difluoro-5-methoxycarbonyloxy-1-nitrobenzene (2.7 g, 0.012 mol) and 10% palladium-on-charcoal catalyst (500 mg) in ethanol (20 ml) and ethyl acetate (10 ml) was stirred under 1 atmosphere of hydrogen for 4 hours. The catalyst was removed by filtration through diatomaceous earth and the solvent removed by evaporation to give 2,4-difluoro-5-methoxycarbonyloxyaniline (2.3 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06184225B2 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-a4780ae330834eaeaed3a048c4fd9b8b |
| Source note | uspto-grants-2001_02 |