Benzenebutanamine → HCID 21260503, compound

HRID 634766Notes

Reaction equation

HRID 634766 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH2:14][CH2:13][CH2:12][CH:11]([NH:15][CH2:16][CH2:17][CH:18](C3C=CC=CC=3)[CH3:19])[CH:10]=2)=[CH:5][CH:4]=1.CO[C:28]1[CH:33]=[CH:32][C:31](C2CCCC(=O)C=2)=[CH:30][CH:29]=1.C1(CCCCN)C=CC=CC=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH2:14][CH2:13][CH2:12][CH:11]([NH:15][CH2:16][CH2:17][CH2:18][CH2:19][C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[CH:10]=2)=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 83242BenzenebutanamineHCID 3679273-(4-Methoxyphenyl)-2-cyclohexen-1-oneHCID 21260554HCID 21260554, compound

Product 1

HCID 21260503HCID 21260503, compound

Procedure

Following the general procedure of example 28, (RS)-[3-(4-methoxy-phenyl)-cyclohex-2-enyl]-(3-phenyl-butyl)-amine (2.8 g; 56% light yellow oil, MS: m/e=336.2 (M+H+)) was prepared from 3-(4-methoxy-phenyl)-cyclohex-2-enone (3.0 g; 14.8 mmol) and 4-phenyl-butylamine (2.21 g; 14.8 mmol).

Sources & evidence

ORD record
ord-7792b7dee6e248538c70a09f040ae0e7
Source dataset
uspto-grants-2001_02
Patent number
US06184236B2

Reaction notes

Loading…