HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 4-(4'-Hydroxyphenyl)-2-butanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Paclitaxel | HCID 36314 | — |
| Product | 4-(4'-Hydroxyphenyl)-2-butanone | HCID 21648 | — |
Reaction Steps
Taxus wallichiana known as the Himalayan yew is available in India. The applicants have investigating the different parts of this plant from different Himalayan regions of India for isolation of naturally occurring analogues of taxol, its important precursors and other biologically active compounds. During the course of investigation the applicants have isolated 2 compounds of 4-aryl-2-butanol namely betuligenol having formula C10H14O2, mp 69-70° C., [α]n+20 (C1, MeOH) and betuliloside having formula C16H24O7 mp 187-188°, [α]n+22° (C1, MeOH) from the leaves of T. wallichiana.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06184367B2 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-155f7e0dea044e9eaeba54feb561dae2 |
| Source note | uspto-grants-2001_02 |