Trifluoroacetic acid → HCID 20639712, compound

Participants

Reaction Steps

Treatment of N-[(1-methyl-3-isobutyl-indole-2-carbonyl)valinyl]-3-amino-4-oxo-5-(2-fluorophenyloxy)-pentanoic acid, tert-butyl ester (76 mg, 0.124 mmol) with TFA as described in Example 80 gave the titled product (25.0 mg, 36%) as a white powder. MS C30H36FN3O6, [M+Na]+ =554, [M−H]− =552. TLC (hexane/EtOAc, 50/50): Rf=0.21.

Provenance & Evidence