HCID 69961821, compound → HCID 69963903, compound

HRID 635138Notes

Reaction equation

HRID 635138 reaction equation
[CH2:1]([O:6][C:7]1[CH:8]=[N:9][C:10]([C:13]2[CH:18]=[CH:17][C:16]([C:19]34[CH2:26][CH2:25][C:22]([CH2:27][CH2:28][CH3:29])([CH2:23][CH2:24]3)[CH2:21][CH2:20]4)=[CH:15][CH:14]=2)=[N:11][CH:12]=1)/[CH:2]=[CH:3]/[CH2:4]C.C(OC1C=NC(C2C=CC(C34CCC(CCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CCC.C(OC1C=NC(C2C=CC(C34CCC(CCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CCCC.C(OC1C=NC(C2C=CC(C34CCC(CCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CCCCC.C(OC1C=NC(C2C=CC(C34CCC(CCCCC)(CC3)CC4)=CC=2)=NC=1)/C=C/C.C(OC1C=NC(C2C=CC(C34CCC(CCCCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CC.C(OC1C=NC(C2C=CC(C34CCC(CCCCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CCCC.C(OC1C=NC(C2C=CC(C34CCC(CCCCCCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CCCCC.C(OC1C=NC(C2C=CC(C34CCC(CCCCCCC)(CC3)CC4)=CC=2)=NC=1)/C=C/C.C(OC1C=NC(C2C=CC(C34CCC(CCCCCCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CC.C(OC1C=NC(C2C=CC(C34CCC(CCCCCCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CCC.C(OC1C=NC(C2C=CC(C34CCC(CCCCCCC)(CC3)CC4)=CC=2)=NC=1)/C=C/CCCC>>[CH2:1]([O:6][C:7]1[CH:12]=[N:11][C:10]([C:13]2[CH:14]=[CH:15][C:16]([C:19]34[CH2:24][CH2:23][C:22]([CH2:27][CH2:28][CH3:29])([CH2:21][CH2:20]3)[CH2:25][CH2:26]4)=[CH:17][CH:18]=2)=[N:9][CH:8]=1)/[CH:2]=[CH:3]/[CH3:4]

Participants

13

Reactant 12

HCID 69961821HCID 69961821, compoundHCID 69962574HCID 69962574, compoundHCID 69962581HCID 69962581, compoundHCID 69962884HCID 69962884, compoundHCID 69963270HCID 69963270, compoundHCID 69963325HCID 69963325, compound2×HCID 69963713HCID 69963713, compoundHCID 69964062HCID 69964062, compoundHCID 69964578HCID 69964578, compoundHCID 69964595HCID 69964595, compoundHCID 69965319HCID 69965319, compoundHCID 70223909HCID 70223909, compound

Product 1

HCID 69963903HCID 69963903, compound

Procedure

1-[4-(5-[(E)-Pent-2-enyloxy]pyrimidin-2-yl)phenyl]-4-propylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Hex-2-enyloxy]pyrimidin-2-yl)phenyl]-4-propylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Hept-2-enyloxy]pyrimidin-2-yl)phenyl]-4-propylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Oct-2-enyloxy]pyrimidin-2-yl)phenyl]-4-propylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-But-2-enyloxy]pyrimidin-2-yl)phenyl]-4-pentylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Pent-2-enyloxy]pyrimidin-2-yl)phenyl]-4-pentylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Hept-2-enyloxy]pyrimidin-2-yl)phenyl]-4-pentylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Oct-2-enyloxy]pyrimidin-2-yl)phenyl]-4-heptylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-But-2-enyloxy]pyrimidin-2-yl)phenyl]-4-heptylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Pent-2-enyloxy]pyrimidin-2-yl)phenyl]-4-heptylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Hex-2-enyloxy]pyrimidin-2-yl)phenyl]-4-heptylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Hept-2-enyloxy]pyrimidin-2-yl)phenyl]-4-heptylbicyclo[2.2.2]octane. 1-[4-(5-[(E)-Oct-2-enyloxy]pyrimidin-2-yl)phenyl]-4-heptylbicyclo[2.2.2]octane.

Sources & evidence

ORD record
ord-69b7f5b77a9f4503b2da69d5ef0d3c5c
Source dataset
uspto-grants-2001_02
Patent number
US06187393B1

Reaction notes

Loading…