HCID 54273954, compound → HCID 53764495, compound

HRID 635165Notes

Reaction equation

HRID 635165 reaction equation
[C:1]([NH:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@@H:9]([O:15][C:16](=[O:18])[CH3:17])[C@@H:8]([CH2:19][O:20][C:21](=[O:23])[CH3:22])[O:7][C@@H:6]1[N:24]=[N+]=[N-])(=[O:3])[CH3:2]>CO.[Pd]>[C:1]([NH:4][C@@H:5]1[C@@H:10]([O:11][C:12](=[O:14])[CH3:13])[C@@H:9]([O:15][C:16](=[O:18])[CH3:17])[C@@H:8]([CH2:19][O:20][C:21](=[O:23])[CH3:22])[O:7][C@@H:6]1[NH2:24])(=[O:3])[CH3:2]

Participants

4

Reactant 1

HCID 54273954HCID 54273954, compound

Product 1

HCID 53764495HCID 53764495, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Compound 47 (1.0 g) was dissolved in 30 mL methanol and subjected to hydrogenolysis using 1.0 g of 10% Pd on activated charcoal. After 24 hr, the charcoal was removed by filtration, and the filtrate was concentrated under vacuum to give 2-acetamido-3,4,6-tri-O-acetyl-1-amino-1,2-dideoxy-a-D-galactopyranose, 48, as colorless gum (850 mg). The derivative 48 gave a positive ninhydrin test.

Workup

  1. customthe charcoal was removed by filtration
  2. concentrationthe filtrate was concentrated under vacuum

Sources & evidence

ORD record
ord-b4a097dfade84c68b137da51ca27f5af
Source dataset
uspto-grants-2001_02
Patent number
US06187762B1

Reaction notes

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