HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 18328113, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-Bromo-4-chlorobutane | HCID 81364 | — |
| Reactant | HCID 18328025 | HCID 18328025 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18328113 | HCID 18328113 | — |
Reaction Steps
430 mg of 4,5-dihydro-3-ethyl-1,4-benzoxazepin-5-one was dissolved in 10 ml of dimethylformamide, then 110 mg (1.2 equivalents) of 60% sodium hydride was added under ice cooling. This was agitated for 30 minutes, then 480 mg (1.2 equivalents) of 1-bromo-4-chlorobutane was added and the resultant mixture was agitated at room temperature for 6 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06187769B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-710e0aebee904cff96c7f49c3f2a00e4 |
| Source note | uspto-grants-2001_02 |