HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cycloheptanone Oxime → 3-(3-(4-(4-chloro-3-trifluoromethylphenyl)piperidin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cycloheptanone Oxime | HCID 137457 | — |
| Reactant | Ethyl 4-(4-(4-chloro-3-trifluoromethylphenyl)piperidin-1-yl)-n-butyrate | HCID 17773233 | — |
| Product | 3-(3-(4-(4-chloro-3-trifluoromethylphenyl)piperidin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole | HCID 59939392 | — |
Reaction Steps
By the same reaction and treatment as in Example 48 using cycloheptanone oxime and ethyl 4-(4-(4-chloro-3-trifluoromethylphenyl)piperidin-1-yl)-n-butyrate, 3-(3-(4-(4-chloro-3-trifluoromethylphenyl)piperidin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06187774B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-7bedf3ab28244d278589f7af7e56eaa4 |
| Source note | uspto-grants-2001_02 |