Cycloheptanone Oxime → HCID 59939415, compound

HRID 635280Notes

Reaction equation

HRID 635280 reaction equation
[C:1]1(=[N:8][OH:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:10][C:11]1[C:16]([Cl:17])=[CH:15][CH:14]=[CH:13][C:12]=1[CH:18]1[CH2:23][CH2:22][N:21]([CH2:24][CH2:25][CH2:26][C:27](OCC)=O)[CH2:20][CH2:19]1>>[Cl:10][C:11]1[C:16]([Cl:17])=[CH:15][CH:14]=[CH:13][C:12]=1[CH:18]1[CH2:23][CH2:22][N:21]([CH2:24][CH2:25][CH2:26][C:27]2[O:9][N:8]=[C:1]3[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]=23)[CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 137457Cycloheptanone OximeHCID 17773129HCID 17773129, compound

Product 1

HCID 59939415HCID 59939415, compound

Procedure

By the same reaction and treatment as in Example 48 using cycloheptanone oxime and ethyl 4-(4-(2,3-dichlorophenyl)piperidin-1-yl)-n-butyrate, 3-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole is obtained.

Sources & evidence

ORD record
ord-2eced664f071400a9f3c4380097333f3
Source dataset
uspto-grants-2001_02
Patent number
US06187774B1

Reaction notes

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