Cycloheptanone Oxime → HCID 59939380, compound

HRID 635287Notes

Reaction equation

HRID 635287 reaction equation
[C:1]1(=[N:8][OH:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]2[CH2:18][CH2:19][N:20]([CH2:23][CH2:24][CH2:25][C:26](OCC)=O)[CH2:21][CH:22]=2)=[CH:13][CH:12]=1>>[Br:10][C:11]1[CH:16]=[CH:15][C:14]([C:17]2[CH2:22][CH2:21][N:20]([CH2:23][CH2:24][CH2:25][C:26]3[O:9][N:8]=[C:1]4[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]=34)[CH2:19][CH:18]=2)=[CH:13][CH:12]=1

Participants

3

Procedure

By the same reaction and treatment as in Example 48 using cycloheptanone oxime and ethyl 4-(4-(4-bromophenyl)-1,2,3,6-tetrahydropyridin-1-yl)-n-butyrate, 3-(3-(4-(4-bromophenyl)-1,2,3,6-tetrahydropyridin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole is obtained.

Sources & evidence

ORD record
ord-c8e98ad1d12a4ba6b7c330066d8c6600
Source dataset
uspto-grants-2001_02
Patent number
US06187774B1

Reaction notes

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