Cycloheptanone Oxime → HCID 59939370, compound

HRID 635291Notes

Reaction equation

[C:1]1(=[N:8][OH:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][C:11]=1[C:20]1[CH2:21][CH2:22][N:23]([CH2:26][CH2:27][CH2:28][C:29](OCC)=O)[CH2:24][CH:25]=1>>[CH:10]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:13]=[CH:12][C:11]=1[C:20]1[CH2:25][CH2:24][N:23]([CH2:26][CH2:27][CH2:28][C:29]2[O:9][N:8]=[C:1]3[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]=23)[CH2:22][CH:21]=1

Participants

Reactant 2

HCID 137457Cycloheptanone Oxime

HCID 17773171HCID 17773171, compound

Product 1

HCID 59939370HCID 59939370, compound

Procedure

By the same reaction and treatment as in Example 48 using cycloheptanone oxime and ethyl 4-(4-(2-naphthyl)-1,2,3,6-tetrahydropyridin-1-yl)-n-butyrate, 3-(3-(4-(2-naphthyl)-1,2,3,6-tetrahydropyridin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole is obtained.

Sources & evidence

ORD record: ord-7da495f075914b1196c19eb290807217
Source dataset: uspto-grants-2001_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06187774B1

Reaction notes

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