N-Thian-4-ylidenehydroxylamine → HCID 17773202, compound

HRID 635295Notes

Reaction equation

HRID 635295 reaction equation
[S:1]1[CH2:6][CH2:5][C:4](=[N:7][OH:8])[CH2:3][CH2:2]1.[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([N:16]2[CH2:21][CH2:20][N:19]([CH2:22][CH2:23][CH2:24][C:25](OCC)=O)[CH2:18][CH2:17]2)=[CH:12][CH:11]=1>>[Cl:9][C:10]1[CH:11]=[CH:12][C:13]([N:16]2[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][CH2:24][C:25]3[O:8][N:7]=[C:4]4[CH2:3][CH2:2][S:1][CH2:6][C:5]=34)[CH2:20][CH2:21]2)=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 237774N-Thian-4-ylidenehydroxylamineHCID 17773218HCID 17773218, compound

Product 1

HCID 17773202HCID 17773202, compound

Procedure

By the same reaction and treatment as in Example 48 using tetrahydro-4H-thiopyran-4-one oxime and ethyl 4-(4-(4-chlorophenyl)piperazin-1-yl)-n-butyrate, 3-(3-(4-(4chlorophenyl)piperazin-1-yl)propyl)-6,7-dihydro-4H-thiopyrano[4,3-c]isoxazole is obtained.

Sources & evidence

ORD record
ord-aa0d8041c4e446ddbd2aa981b4479912
Source dataset
uspto-grants-2001_02
Patent number
US06187774B1

Reaction notes

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