Cyclohexanone Oxime → HCID 17773122, compound
Reaction equation
[C:1]1(=[N:7][OH:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][CH2:24][C:25](OCC)=O)[CH2:20][CH:21]=2)=[CH:12][CH:11]=1>>[Cl:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH2:21][CH2:20][N:19]([CH2:22][CH2:23][CH2:24][C:25]3[O:8][N:7]=[C:1]4[CH2:6][CH2:5][CH2:4][CH2:3][C:2]=34)[CH2:18][CH:17]=2)=[CH:12][CH:11]=1Participants
3
Procedure
By the same reaction and treatment as m Example 48 using cyclohexanone oxime and ethyl 4-(4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridin-1-yl)-n-butyrate, 3-(3-(4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridin-1-yl)propyl)-4,5,6,7-tetrahydrobenzo[c]isoxazole is obtained.
Sources & evidence
- ORD record
- ord-eb385fe6c42d47cc8998bd9d9473891a
- Source dataset
- uspto-grants-2001_02
- Patent number
- US06187774B1
Reaction notes
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