Cyclohexanone Oxime → HCID 17773099, compound

HRID 635303Notes

Reaction equation

HRID 635303 reaction equation
[C:1]1(=[N:7][OH:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:9][C:10]1[CH:15]=[CH:14][C:13]([N:16]2[CH2:21][CH2:20][N:19]([CH2:22][CH2:23][CH2:24][C:25](OCC)=O)[CH2:18][CH2:17]2)=[CH:12][CH:11]=1>>[CH3:9][C:10]1[CH:11]=[CH:12][C:13]([N:16]2[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][CH2:24][C:25]3[O:8][N:7]=[C:1]4[CH2:6][CH2:5][CH2:4][CH2:3][C:2]=34)[CH2:20][CH2:21]2)=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 7517Cyclohexanone OximeHCID 12234159HCID 12234159, compound

Product 1

HCID 17773099HCID 17773099, compound

Procedure

By the same reaction and treatment as in Example 48 using cyclohexanone oxime and ethyl 4-(4-(4-methylphenyl)piperazin-1-yl)-n-butyrate, 3-(3-(4-(4-methylphenyl)piperazin-1-yl)propyl)-4,5,6,7-tetrahydrobenzo[c]isoxazole is obtained.

Sources & evidence

ORD record
ord-6da65d9e05d1478cade8fb2ee84231d2
Source dataset
uspto-grants-2001_02
Patent number
US06187774B1

Reaction notes

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