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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 635305Generated: October 25, 2026

Cycloheptanone Oxime → 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole

https://huagongshe.com/reaction/635305

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCycloheptanone OximeHCID 137457—
ReactantEthyl 4-(4-(4-fluorophenyl)piperazin-1-yl)-n-butyrateHCID 14879737—
Product3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazoleHCID 59939390—

Reaction Steps

By the same reaction and treatment as in Example 48 using cycloheptanone oxime and ethyl 4-(4-(4-fluorophenyl)piperazin-1-yl)-n-butyrate, 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-5,6,7,8-tetrahydro-4H-cyclohepta[c]isoxazole is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06187774B1
Source datasetuspto-grants-2001_02
ORD IDord-8eaf9fdf7459475f955d69283930761d
Source noteuspto-grants-2001_02