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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 635306Generated: October 29, 2026

2,2-Dimethyl-1,3-dioxane-4,6-dione → 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepine

https://huagongshe.com/reaction/635306

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 16249—
Reactant1-(4-Fluorophenyl)piperazineHCID 75260—
Reactant6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepineHCID 10261149—
Product3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepineHCID 59939437—

Reaction Steps

By the same reaction and treatment as in Example 91 using 6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepine, 2,2-dimethyl-1,3-dioxane-4,6-dione and 1-(4-fluorophenyl)piperazine, 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepine is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06187774B1
Source datasetuspto-grants-2001_02
ORD IDord-966188ef598942ec84226cd69ab42ffc
Source noteuspto-grants-2001_02