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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 635327Generated: October 31, 2026

Hydrochloric Acid → HCID 178478549, compound

https://huagongshe.com/reaction/635327

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1-(4-Chlorophenyl)piperazineHCID 97478—
Reactant4-(4-Chlorophenyl)piperidineHCID 1203613—
Reactant3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propanoic acidHCID 178525369—
ProductHCID 178478549HCID 178478549—

Reaction Steps

In the same manner as in Example 102 except that 3-(2,4,5,6-tetrahydrocyclopentapyrazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 4 and 1-(4-chlorophenyl)piperazine were used instead of 3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 1 and 4-(4-chlorophenyl)piperidine, and then by a conventional treatment using hydrochloric acid, 3-(3-(4-(4-chlorophenyl)piperazin-1-yl)propyl)-2,4,5,6-tetrahydrocyclopentapyrazole hydrochloride was obtained, m.p. 228-230° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06187774B1
Source datasetuspto-grants-2001_02
ORD IDord-b0b5e759fddb4c08af0407e77d7b7457
Source noteuspto-grants-2001_02