Ethyl 2-(oxetan-3-ylidene)propanoate → Ethyl 2-(oxetan-3-yl)propanoate

Beteiligte Stoffe

Reaktionsschritte

To a solution of (i) (151 mg, 0.97 mmol) in EtOH (54 mL) was added 10% Pd/C (50 mg, 0.05 mmol). The reaction was degassed and purged with hydrogen at balloon pressure (×3) then stirred under hydrogen at RT for 16 h. The reaction mixture was filtered and the residue washed with acetonitrile (10 mL). The combined organics were concentrated in vacuo and the residue, (ii) (148 mg), was used without further purification.

Herkunft & Nachweise